Many journal publishers do analyze submitted manuscripts using the iThenticate service, including the American Physical Society (APS), IEEE, Springer-Nature, Elsevier, Public Library of Science (PLoS), and many others. The version of iThenticate that the publishers use is commonly called "CrossCheck", and is part of the publisher services that the DOI Registration Agency CrossRef offers as a value added benefit. When publishers register a DOI for a given article, they submit it for iThenticate similarity checking and also agree to add the published article to the iThenticate database. In this way, the iThenticate database of content being checked for similarity is continuously updated with new papers, proceedings, and books/book chapters.
if you wish to know whether a particular publication is included in the iThenticate database, visit the online page at https://www.ithenticate.com/search?q= and type in the title of interest in the the ‘search scholarly journals’ box in the middle of the page (example shown below). If the database includes the journal, the results will display the name of the journal, the publisher, and the number of articles that iThenticate includes.
According to a study commissioned by the international Committee on Publication Ethics (COPE), over 40% of journal editors worldwide screen manuscript submissions against the iThenticate database. They do this via the CrossCheck service - the publisher-facing version of iThenticate available from the DOI agency CrossRef.
An example of a publisher's policies using CrossCheck/iThenticate is available in the Springer Nature CrossCheck Guide online at https://www.springer.com/gp/authors-editors/plagiarism-prevention-with-crosscheck/1214.
In another example, Elsevier has integrated CrossCheck and iThenticate into their editorial submission system to ensure that all manuscripts are checked. Yet Elsevier editors understand the importance of combining the generated similarity reports with sound judgment. As explained by one of their editors-in-chief, commenting in "How CrossCheck can combat the perils of plagiarism": "t depends very much on whose text is reused and in which part of the paper. There's a big difference between similarities in the research methodology descriptions and the actual research findings.
iThenticate relies on an extensive and growing database of research documents from 3 sources, including premium scholarly publications, the Intenet Archive, and a global student papers database. (An updated description of these sources is available from iThenticate at https://www.ithenticate.com/content and Databases Content (PDF))
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(3) Web pages crawled by iThenticate's own search engine, with content dating back at least a decade and being updated daily.
it is important to keep in mind that iThenticate's repository is not complete -- the Similarity Report and Similarity Score reflect matches only to documents contained in iThenticate's repository.
You may wish to check the Author Guidelines for the publisher or journal of interest to see if they mention iThenticate or CrossCheck or CrossRef Similarity Check.
The publisher website may include an iThenticate badge such as this:
For example, the Copernicus website at https://www.publications.copernicus.org/services/plagiarism_detection.html clearly indicates use of iThenticate.